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KMID : 1011920170180010016
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International Journal of Arrhythmia
2017 Volume.18 No. 1 p.16 ~ p.26
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The Impact of the CHA2 DS2-VASc Score on Recurrence of Atrial Fibrillation after a Single Catheter Ablation and Atrial Remodeling in Patients with Non-Valvular Atrial Fibrillation
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Lee Chan-Hee
Lee Sang-Hee
Park Kyu-Hwan
Shin Dong-Gu
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Abstract
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Background and Objectives: This study aimed to evaluate the impact of the CHA2 DS2-VASc score on atrial fibrillation (AF) recurrence after a single catheter ablation procedure in patients with non-valvular AF. We also investigated the correlation between CHA2 DS2-VASc score and atrial substrate.
Subjects and Methods: This study evaluated 151 patients who underwent catheter ablation of non-valvular AF. The study population was stratified into group 1 (<2, n=72) and group 2 (≥2, n=79) by CHA2 DS2-VASc score. The CHA2 DS2-VASc score was analyzed as a continuous and categorical value for evaluating its impact on AF recurrence after catheter ablation. The left atrial voltage data were analyzed by the categorical values of this score.
Results: Post-ablation recurrence (31.6% vs. 18.1%, p=0.046) was observed more frequently in group 2. The mean area of the low-voltage zone was 75.64±24.81 cm2 and 94.44±28.09 cm2 in groups 1 and 2, respectively (p=0.005). The left atrial mean voltage in group 2 was 0.99±0.31 mV, significantly lower than that (1.49±0.67 mV, p=0.001) in group 1. The CHA2 DS2-VASc score was the independent predictor with a modest predictive value for AF recurrence after catheter ablation.
Conclusion: Our study showed that CHA2 DS2-VASc score was associated with atrial remodeling and could be useful in stratifying post-ablation recurrence in patients with non-valvular AF.
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KEYWORD
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Atrial Fibrillation, Catheter Ablation, Recurrence, Atrial Remodeling
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